Yojimbo usually attacks using his dog Daigoro, though he may occasionally attack with Kozuka and Wakizashi when low on HP. Yojimbo's Overdrive charges on his turn and whenever he is attacked. When full, he will unleash Zanmato, which inflicts 9,999 points of damage on all party members. The player can avoid this by sacrificing an aeon.
The player can defeat Yojimbo by inflicting the Doom status on him. This can be done either by Kimahri using the Ronso RageDoom, which can be learned from the Ghosts inhabiting the cavern, or by using a Candle of Life. Yojimbo will then be defeated within five turns. This strategy only works for the encounter in the Cavern of the Stolen Fayth.