- "There's an ailment called 'Disease', very nasty. Once you get that in your system, your wounds... they won't heal."
- —Wounded Refugee, Mt. Bur-Omisace in Final Fantasy XII
Virus (ウイルス, Uirusu?), sometimes called Disease or Pointless, is a negative status effect appearing in various games. It is normally not visible during a fight except by checking a character's status in a menu during the fight.
|Virus Combo||Enemy Attack||Inflicts moderate non-elemental damage and Virus.|
|Virus Crunch||Enemy Attack||Inflicts major non-elemental damage and Virus.|
|Virus Fly||Enemy Attack||Inflicts major non-elemental damage and Virus.|
|Virus Powder||Enemy Attack||Inflicts major non-elemental damage and Virus.|
|Viral Smoke||Enemy Attack||Inflicts moderate non-elemental damage and Virus to party.|
|Virus Tentacle||Enemy Attack||Inflicts major non-elemental damage and Virus.|
Pointless prohibits a character from earning experience and Ability Points. It can be cured with Holy Water.
Virus (divided into Plague or Disease) appears in Final Fantasy XI; It inhibits the regeneration of HP and MP through Healing. Players can still gain some HP and MP through Cures, Regen, and Refresh, as well as items that grant similar bonuses, however. The variation effect Plague instead slowly saps MP and TP until it wears off. Both status effects can be removed by casting Viruna on the inflicted.
- "The character's body festers with disease, preventing the healing of wounds. Remove with a Vaccine."
Disease prohibits the use of healing items and magicks on a character. It does this in an odd way, by turning a character's Current HP into their new Maximum HP after receiving damage. Enemies usually combine Disease with Poison and/or Sap which will eventually reduce character's hit-point to only 1/1 (in such state, character is not regarded as critical).
Disease is cured with a Vaccine, the White Magicks Cleanse and Regen, or a Remedy, provided the character has the license, Remedy Lore 3. Characters who are currently in Bubble status will be immune to Disease. A KO'd character with Disease status will have only 1/1 HP if he/she was revived. A character can inflict Disease on enemies by using Vaccine or Remedy only if that character has the accessory Nihopalaoa equipped.
In the International Zodiac Job System edition, a newly included mace "Guriguri Banban" can inflict Disease along with Sap while attacking with 100% success rate. It is a vital weapon for the 100th stage of the Trial Mode.