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Debuffs work quite well on the Sacrifices and help to keep them under control, especially in larger groups. A Cherub's Crown or the upgraded Seraph's Crown can be equipped for protection against the Death spell these enemies can cast, although Death has a low base chance of hitting. Players should be aware of Sacrifice's Anathema ability, which can inflict several status ailments.
Sacrifices often drop Perfume, an item which can be sold for 12,500 gil. These enemies rarely drop Scarletite, an upgrade catalyst, but they are also useful for obtaining gil, selling for 7,000 gil each.
Sacrifices are a considerable source for obtaining gil at the game's end, as they are easy to defeat in comparison to stronger enemies such as the Adamantoise. Sacrifices also appear in larger numbers, resulting in better drop chances.
It is a good idea to equip a Collector Catalog and Connoisseur Catalog to further increase the odds of obtaining Perfumes and Scarletites.
- Sacrifices are similar in appearance to Cid Raines's Cie'th-human hybrid form (due to their metallic, silver bodies, and long, black claws). This may be due to their mutual nature as Sanctum l'Cie that later became Cie'th.
- It is the only enemy in the game that uses a full ATB skill, specifically, Death.