Gilgamesh may refer to:
- The recurring character.
- The enemy from Final Fantasy IV.
- The monster name from Final Fantasy XIII-2.
Gilgamesh is the main character of the Epic of Gilgamesh, an Akkadian poem considered the first great work of literature. He is a demigod with superhuman strength who builds the walls of Uruk to defend his people and travels to meet the sage Utnapishtim, a survivor of the Great Flood.
Gilgamesh is believed to have actually existed by many scholars. It is estimated he lived sometime between 2800 and 2500 BC. The Sumerian King List claims Gilgamesh ruled the city of Uruk for 126 years.