Confrontation is a status ailment in Final Fantasy XI that forces a confrontation between a character or Party of characters and a specific monster or group of monsters. It does this by preventing the player from receiving external aid, or from attacking or affecting monsters other than the specially designated monsters—such actions simply are not allowed to occur. Also, when Confrontation is inflicted, the affected players will have their Pets dismissed.
Confrontation status is gained by initiating certain optional battles—it isn't something that monsters can just randomly inflict in order to make life more difficult. Confrontation cannot be removed by any means other than completing the battle, whether by victory or by defeat.